Expression of the Two Major Envelope Proteins of Equine Arteritis Virus as a Heterodimer Is Necessary for Induction of Neutralizing Antibodies in Mice Immunized with Recombinant Venezuelan Equine Encephalitis Virus Replicon Particles

RNA replicon particles derived from a vaccine strain of Venezuelan equine encephalitis virus (VEE) were used as a vector for expression of the major envelope proteins (G(L) and M) of equine arteritis virus (EAV), both individually and in heterodimer form (G(L)/M). Open reading frame 5 (ORF5) encodes...

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Publicat a:	J Virol
Autors principals:	Balasuriya, Udeni B. R., Heidner, Hans W., Hedges, Jodi F., Williams, Jacqueline C., Davis, Nancy L., Johnston, Robert E., MacLachlan, N. James
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2000
Matèries:	Vaccines and Antiviral Agents
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044106/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10623-10630.2000
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