Efficacy and Safety Studies of a Recombinant Chimeric Respiratory Syncytial Virus FG Glycoprotein Vaccine in Cotton Rats

Several formulations of a recombinant chimeric respiratory syncytial virus (RSV) vaccine consisting of the extramembrane domains of the F and G glycoproteins (FG) were tested in cotton rats to evaluate efficacy and safety. The FG vaccine was highly immunogenic, providing nearly complete resistance t...

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Main Authors: Prince, Gregory A., Capiau, Carine, Deschamps, Marguerite, Fabry, Luc, Garçon, Nathalie, Gheysen, Dirk, Prieels, Jean-Paul, Thiry, Georges, Van Opstal, Omer, Porter, David D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC110902/
https://ncbi.nlm.nih.gov/pubmed/11044072
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