Incorporation of Tumor Vasculature Targeting Motifs into Moloney Murine Leukemia Virus Env Escort Proteins Enhances Retrovirus Binding and Transduction of Human Endothelial Cells

Adhesion receptors expressed on the surfaces of tumor-activated endothelial cells provide an advantageous locus for targeting gene therapy vectors to angiogenic tissues and/or tumor vasculature. In this study, we engineered a series of Asn-Gly-Arg (NGR)-containing congeners of the presumptive cell b...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Liqiong, Liu, Ling, Anderson, W. French, Beart, Robert W., Gordon, Erlinda M., Hall, Frederick L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2000
Gaiak:
Gene Therapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC110887/
https://ncbi.nlm.nih.gov/pubmed/10799609
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