Chimeric Retroviral Helper Virus and Picornavirus IRES Sequence To Eliminate DNA Methylation for Improved Retroviral Packaging Cells

Most retroviral packaging cell lines were established by a helper virus plasmid cotransfected with a separate plasmid encoding a selection marker. Since this selection marker coexisted in trans with the helper virus sequence, helper virus gene expression could be inactivated by host DNA methylation...

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Опубліковано в::	J Virol
Автори:	Young, Won-Bin, Link, Charles J.
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2000
Предмети:	Gene Therapy
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10799600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.11.5242-5249.2000
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