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A Single Amino Acid Change in the Newcastle Disease Virus Fusion Protein Alters the Requirement for HN Protein in Fusion

The role of a leucine heptad repeat motif between amino acids 268 and 289 in the structure and function of the Newcastle disease virus (NDV) F protein was explored by introducing single point mutations into the F gene cDNA. The mutations affected either folding of the protein or the fusion activity...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Sergel, Theresa A., McGinnes, Lori W., Morrison, Trudy G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110862/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10799584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.11.5101-5107.2000
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