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Cytoplasmic Sequestration of Rel Proteins by IκBα Requires CRM1-Dependent Nuclear Export

Rel and IκB protein families form a complex cellular regulatory network. A major regulatory function of IκB proteins is to retain Rel proteins in the cell cytoplasm. In addition, IκB proteins have also been postulated to serve nuclear functions. These include the maintenance of inducible NF-κB-depen...

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Udgivet i:Mol Cell Biol
Principais autores: Tam, Winnie F., Lee, Linda H., Davis, Laura, Sen, Ranjan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Nucleocytoplasmic Communication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688673/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2269-2284.2000
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