p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin

We have characterized the mechanism by which coactivator p300 facilitates transcriptional activation mediated by the heterodimer of thyroid hormone (T3) receptor and 9-cis retinoid acid receptor (TR-RXR) in the context of chromatin. We demonstrate that, while p300 can enhance the transcriptional act...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Li, Jiwen, O'Malley, Bert W., Wong, Jiemin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2031-2042.2000
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