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Pocket Protein-Independent Repression of Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor 1 Gene Expression by E2F1

Expression of genes of the plasminogen activator (PA) system declines at the G(0)/G(1)-S-phase boundary of the cell cycle. We found that overexpression of E2F1-3, which acts mainly in late G(1), inhibits promoter activity and endogenous expression of the urokinase-type PA (uPA) and PA inhibitor 1 (P...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Koziczak, Magdalena, Krek, Wilhelm, Nagamine, Yoshikuni
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2000
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688648/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2014-2022.2000
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