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Mitochondrial DNA ligase III function is independent of Xrcc1

Hamster EM9 cells, which lack Xrcc1 protein, have reduced levels of DNA ligase III and are defective in nuclear base excision repair. The Xrcc1 protein stabilizes DNA ligase III and may even play a direct role in catalyzing base excision repair. Since DNA ligase III is also thought to function in mi...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Lakshmipathy, Uma, Campbell, Colin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.20.3880
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