A pathogenic point mutation reduces stability of mitochondrial mutant tRNA(Ile)

Point mutations in mitochondrial tRNA genes are responsible for individual subgroups of mitochondrial encephalomyopathies. We have recently reported that point mutations in the tRNA(Leu)(UUR) and tRNA(Lys) genes cause a defect in the normal modification at the first nucleotide of the anticodon. As p...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Yasukawa, Takehiro, Hino, Narumi, Suzuki, Tsutomu, Watanabe, Kimitsuna, Ueda, Takuya, Ohta, Shigeo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110767/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11000270/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.19.3779
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