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Telomere repeat DNA forms a large non-covalent complex with unique cohesive properties which is dissociated by Werner syndrome DNA helicase in the presence of replication protein A

We describe the unique structural features of a large telomere repeat DNA complex (TRDC) of >20 kb generated by a simple PCR using (TTAGGG)(4) and (CCCTAA)(4) as both primers and templates. Although large, as determined by conventional agarose gel electrophoresis, the TRDC was found to consist of sh...

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Udgivet i:Nucleic Acids Res
Principais autores: Ohsugi, Itaru, Tokutake, Yoshiki, Suzuki, Noriyuki, Ide, Toshinori, Sugimoto, Masanobu, Furuichi, Yasuhiro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110730/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.18.3642
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