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MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase ɛ

MDM2 is induced by p53 in response to cellular insults such as DNA damage and can have effects upon the cell cycle that are independent or downstream of p53. We used a yeast two-hybrid screen to identify proteins that bind to MDM2 and which therefore might be involved in these effects. We found that...

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Udgivet i:Nucleic Acids Res
Principais autores: Vlatkovic, Nikolina, Guerrera, Stephanie, Li, Ying, Linn, Stuart, Haines, Dale S., Boyd, Mark T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982879/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.18.3581
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