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Vaccinia topoisomerase and Cre recombinase catalyze direct ligation of activated DNA substrates containing a 3′-para-nitrophenyl phosphate ester

DNA topoisomerases and DNA site-specific recombinases are involved in a diverse set of cellular processes but both function by making transient breaks in DNA. Type IB topoisomerases and tyrosine recombinases cleave DNA by transesterification of an active site tyrosine to generate a DNA–3′-phosphotyr...

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Bibliografiske detaljer
Main Authors: Woodfield, George, Cheng, Chonghui, Shuman, Stewart, Burgin, Alex B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110714/
https://ncbi.nlm.nih.gov/pubmed/10954601
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