Alternative Splicing Variants of IκBβ Establish Differential NF-κB Signal Responsiveness in Human Cells

To release transcription factor NF-κB into the nucleus, the mammalian IκB molecules IκBα and IκBβ are inactivated by phosphorylation and proteolytic degradation. Both proteins contain conserved signal-responsive phosphorylation sites and have conserved ankyrin repeats. To confer specific physiologic...

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Bibliografiske detaljer
Main Authors: Hirano, Fuminori, Chung, Mirra, Tanaka, Hirotoshi, Maruyama, Naoki, Makino, Isao, Moore, David D., Scheidereit, Claus
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110639/
https://ncbi.nlm.nih.gov/pubmed/9566879
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