Construction and Characterization of Hexon-Chimeric Adenoviruses: Specification of Adenovirus Serotype

This study has used the strategy of gene replacement to characterize the contribution of the adenovirus (Ad) capsid protein hexon to serotype definition. By replacing the Ad type 5 (Ad5) hexon gene with sequences from Ad2, we have changed the type specificity of the chimeric virus. The type-determin...

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Bibliographic Details
Main Authors: Gall, Jason G. D., Crystal, Ronald G., Falck-Pedersen, Erik
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110610/
https://ncbi.nlm.nih.gov/pubmed/9811772
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