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A Conformation-Specific Monoclonal Antibody Reacting with Fusion-Active gp41 from the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

The gp41 subunit of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein plays a major role in the membrane fusion step of viral infection. The ectodomain of gp41 contains a six-helix structural domain that likely represents the core of the fusion-active conformation of the molecule...

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Bibliographic Details
Published in:J Virol
Main Authors: Jiang, Shibo, Lin, Kang, Lu, Min
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110570/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811763/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.10213-10217.1998
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