CCR5- and CXCR4-Utilizing Strains of Human Immunodeficiency Virus Type 1 Exhibit Differential Tropism and Pathogenesis In Vivo

CCR5-utilizing (R5) and CXCR4-utilizing (X4) strains of human immunodeficiency virus type 1 (HIV-1) have been studied intensively in vitro, but the pathologic correlates of such differential tropism in vivo remain incompletely defined. In this study, X4 and R5 strains of HIV-1 were compared for trop...

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Main Authors: Berkowitz, Robert D., Alexander, Sabina, Bare, Cris, Linquist-Stepps, Valerie, Bogan, Mark, Moreno, Mary E., Gibson, Lisa, Wieder, Eric D., Kosek, Jon, Stoddart, Cheryl A., McCune, Joseph M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Viral Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110545/
https://ncbi.nlm.nih.gov/pubmed/9811751
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