Differential Intracellular Compartmentalization of Herpetic Thymidine Kinases (TKs) in TK Gene-Transfected Tumor Cells: Molecular Characterization of the Nuclear Localization Signal of Herpes Simplex Virus Type 1 TK

The thymidine kinases (TKs) of herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV) were expressed in human osteosarcoma cells as fusion proteins with the green fluorescent protein (GFP), and their intracellular localizations were determined. The three TK-GFP fusion products...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Degrève, Bart, Johansson, Magnus, De Clercq, Erik, Karlsson, Anna, Balzarini, Jan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.9535-9543.1998
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