Woodchuck Hepatitis Virus Enhancer I and Enhancer II Are Both Involved in N-myc2 Activation in Woodchuck Liver Tumors

Direct activation of the N-myc2 oncogene by insertion of woodchuck hepatitis virus (WHV) DNA is a major oncogenic step in woodchuck hepatocarcinogenesis. We previously reported that WHV enhancer II (We2), which controls expression of the core/pregenome RNA, can also activate the N-myc2 promoter in h...

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Pubblicato in:	J Virol
Autori principali:	Flajolet, Marc, Tiollais, Pierre, Buendia, Marie-Annick, Fourel, Geneviève
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Viral and Cellular Oncogenes
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621085/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.6175-6180.1998
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