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The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1

Human immunodeficiency virus type 1 (HIV-1) enters target cells by sequential binding to CD4 and specific seven-transmembrane-segment (7TMS) coreceptors. Viruses use the chemokine receptor CCR5 as a coreceptor in the early, asymptomatic stages of HIV-1 infection but can adapt to the use of other rec...

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Autors principals: Choe, Hyeryun, Farzan, Michael, Konkel, Miriam, Martin, Kathleen, Sun, Ying, Marcon, Luisa, Cayabyab, Mark, Berman, Michael, Dorf, Martin E., Gerard, Norma, Gerard, Craig, Sodroski, Joseph
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC110417/
https://ncbi.nlm.nih.gov/pubmed/9621075
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