Exclusive and Persistent Use of the Entry Coreceptor CXCR4 by Human Immunodeficiency Virus Type 1 from a Subject Homozygous for CCR5 Δ32

Individuals who are homozygous for the 32-bp deletion in the gene coding for the chemokine receptor and major human immunodeficiency virus type 1 (HIV-1) coreceptor CCR5 (CCR5 −/−) lack functional cell surface CCR5 molecules and are relatively resistant to HIV-1 infection. HIV-1 infection in CCR5 −/...

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Autori principali: Michael, Nelson L., Nelson, Julie A. E., KewalRamani, Vineet N., Chang, George, O’Brien, Stephen J., Mascola, John R., Volsky, Barbara, Louder, Mark, White, Gilbert C., Littman, Dan R., Swanstrom, Ronald, O’Brien, Thomas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
Soggetti:
Viral Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC110409/
https://ncbi.nlm.nih.gov/pubmed/9621067
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