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Adeno-Associated Virus Vector-Mediated Transgene Integration into Neurons and Other Nondividing Cell Targets

The site-specific integration of wild-type adeno-associated virus (wtAAV) into the human genome is a very attractive feature for the development of AAV-based gene therapy vectors. However, knowledge about integration of wtAAV, as well as currently configured recombinant AAV (rAAV) vectors, is limite...

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Bibliografiske detaljer
Main Authors: Wu, Ping, Phillips, M. Ian, Bui, John, Terwilliger, Ernest F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110396/
https://ncbi.nlm.nih.gov/pubmed/9621054
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