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DNA Packaging Mutant: Repression of the Vaccinia Virus A32 Gene Results in Noninfectious, DNA-Deficient, Spherical, Enveloped Particles

The vaccinia virus A32 open reading frame was predicted to encode a protein with a nucleoside triphosphate-binding motif and a mass of 34 kDa. To investigate the role of this protein, we constructed a mutant in which the original A32 gene was replaced by an inducible copy. The recombinant virus, vA3...

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Detalhes bibliográficos
Main Authors: Cassetti, Maria Cristina, Merchlinsky, Michael, Wolffe, Elizabeth J., Weisberg, Andrea S., Moss, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110378/
https://ncbi.nlm.nih.gov/pubmed/9621036
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