Protective Immunity Induced by Oral Immunization with a Rotavirus DNA Vaccine Encapsulated in Microparticles

DNA vaccines are usually given by intramuscular injection or by gene gun delivery of DNA-coated particles into the epidermis. Induction of mucosal immunity by targeting DNA vaccines to mucosal surfaces may offer advantages, and an oral vaccine could be effective for controlling infections of the gut...

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Hlavní autoři: Chen, Shing C., Jones, David H., Fynan, Ellen F., Farrar, Graham H., Clegg, J. Christopher S., Greenberg, Harry B., Herrmann, John E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Viral Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110376/
https://ncbi.nlm.nih.gov/pubmed/9621034
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