Protective Immunity Induced by Oral Immunization with a Rotavirus DNA Vaccine Encapsulated in Microparticles

DNA vaccines are usually given by intramuscular injection or by gene gun delivery of DNA-coated particles into the epidermis. Induction of mucosal immunity by targeting DNA vaccines to mucosal surfaces may offer advantages, and an oral vaccine could be effective for controlling infections of the gut...

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Autors principals: Chen, Shing C., Jones, David H., Fynan, Ellen F., Farrar, Graham H., Clegg, J. Christopher S., Greenberg, Harry B., Herrmann, John E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Viral Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC110376/
https://ncbi.nlm.nih.gov/pubmed/9621034
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