Murine Coronavirus-Induced Subacute Fatal Peritonitis in C57BL/6 Mice Deficient in Gamma Interferon

Gamma interferon-deficient (IFN-γ−/−) mice with a C57BL/6 background were infected intraperitoneally with mouse hepatitis virus strain JHM (JHMV). In contrast to IFN-γ-+/− and IFN-γ+/+ mice, JHMV persisted in IFN-γ−/− mice and induced death during the subacute phase of the infection. Unexpectedly, i...

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Bibliographic Details
Main Authors: Kyuwa, Shigeru, Tagawa, Yoh-ichi, Shibata, Shinwa, Doi, Kunio, Machii, Kenji, Iwakura, Yoichiroh
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110348/
https://ncbi.nlm.nih.gov/pubmed/9765476
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