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Evidence for an Underlying CD4 Helper and CD8 T-Cell Defect in B-Cell-Deficient Mice: Failure To Clear Persistent Virus Infection after Adoptive Immunotherapy with Virus-Specific Memory Cells from μMT/μMT Mice

Adoptive transfer of virus-specific memory lymphocytes can be used to identify factors and mechanisms involved in the clearance of persistent virus infections. To analyze the role of B cells in clearing persistent infection with lymphocytic choriomeningitis virus (LCMV), we used B-cell-deficient μMT...

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Udgivet i:J Virol
Principais autores: Homann, Dirk, Tishon, Antoinette, Berger, Dietmar P., Weigle, William O., von Herrath, Matthias G., Oldstone, Michael B. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Viral Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.9208-9216.1998
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