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Measles Virus Attenuation Associated with Transcriptional Impediment and a Few Amino Acid Changes in the Polymerase and Accessory Proteins

Measles virus (MV) isolated in B95a cells, a marmoset B-cell line, retains full pathogenicity for cynomolgus monkeys, while its derivative obtained by adaptation to the growth in Vero cells, a monkey kidney cell line, loses the pathogenic potential (F. Kobune, H. Sakata, and A. Sugiura, J. Virol. 64...

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Detalhes bibliográficos
Main Authors: Takeda, Makoto, Kato, Atsushi, Kobune, Fumio, Sakata, Hiroko, Li, Yan, Shioda, Tatsuo, Sakai, Yuko, Asakawa, Makoto, Nagai, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110282/
https://ncbi.nlm.nih.gov/pubmed/9765410
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