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Canine Distemper Virus DNA Vaccination Induces Humoral and Cellular Immunity and Protects against a Lethal Intracerebral Challenge

We have studied the immune responses to the two glycoproteins of the Morbillivirus canine distemper virus (CDV) after DNA vaccination of BALB/c mice. The plasmids coding for both CDV hemagglutinin (H) and fusion protein (F) induce high levels of antibodies which persist for more than 6 months. Intra...

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Autors principals: Sixt, Nathalie, Cardoso, Alicia, Vallier, Agnès, Fayolle, Joël, Buckland, Robin, Wild, T. Fabian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC110255/
https://ncbi.nlm.nih.gov/pubmed/9765383
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