Rabbit Cells Expressing Human CD4 and Human CCR5 Are Highly Permissive for Human Immunodeficiency Virus Type 1 Infection

To evaluate the feasibility of using transgenic rabbits expressing CCR5 and CD4 as a small-animal model of human immunodeficiency virus type 1 (HIV) disease, we examined whether the expression of the human chemokine receptor (CCR5) and human CD4 would render a rabbit cell line (SIRC) permissive to H...

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Main Authors: Speck, Roberto F., Penn, Michael L., Wimmer, Jörg, Esser, Ursula, Hague, Bishop F., Kindt, Thomas J., Atchison, Robert E., Goldsmith, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC110246/
https://ncbi.nlm.nih.gov/pubmed/9621031
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