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Suppression of c-Myc-Induced Apoptosis by the Epstein-Barr Virus Gene Product BHRF1

Constitutive expression of the c-myc proto-oncogene in growth factor-deprived fibroblasts promotes proliferation and induces apoptosis. In these cells, apoptosis can be inhibited by survival factors such as insulin-like growth factor I or the bcl-2 proto-oncogene product. Deregulated c-Myc expressio...

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Autori principali: Fanidi, Abdallah, Hancock, David C., Littlewood, Trevor D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC110225/
https://ncbi.nlm.nih.gov/pubmed/9733891
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