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The Effects of Pharmacological and Lentivirus-Induced Immune Suppression on Orbivirus Pathogenesis: Assessment of Virus Burden in Blood Monocytes and Tissues by Reverse Transcription-In Situ PCR

We investigated the effects of pharmacological and lentivirus-induced immunosuppression on bluetongue virus (BTV) pathogenesis as a mechanism for virus persistence and induction of clinical disease. Immunologically normal and immunosuppressed sheep were infected subcutaneously with BTV serotype 3 (B...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Brodie, Scott J., Wilson, William C., O’Hearn, Patricia M., Muthui, David, Diem, Kurt, Pearson, Leonard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110219/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.5599-5609.1998
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