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Monitoring Retroviral RNA Dimerization In Vivo via Hammerhead Ribozyme Cleavage

We have used a strategy for colocalization of Psi (Ψ)-tethered ribozymes and targets to demonstrate that Ψ sequences are capable of specific interaction in the cytoplasm of both packaging and nonpackaging cells. These results indicate that current in vitro dimerization models may have in vivo counte...

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Bibliographic Details
Main Authors: Pal, Bijay K., Scherer, Lisa, Zelby, Laurie, Bertrand, Edouard, Rossi, John J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110209/
https://ncbi.nlm.nih.gov/pubmed/9733882
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