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The Epstein-Barr Virus Immediate-Early Gene Product, BRLF1, Interacts with the Retinoblastoma Protein during the Viral Lytic Cycle

Retinoblastoma protein (Rb) is a key regulator of cellular proliferation, controlling entry into G(1)/S in the cell cycle, largely through its action in binding the cellular transcription factor E2F, which activates genes important in DNA synthesis. Small DNA tumor viruses encode gene products which...

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Bibliographic Details
Main Authors: Zacny, Valerie L., Wilson, Julie, Pagano, Joseph S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110141/
https://ncbi.nlm.nih.gov/pubmed/9733844
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