The Epstein-Barr Virus Rta Protein Activates Lytic Cycle Genes and Can Disrupt Latency in B Lymphocytes

The transition of Epstein-Barr virus (EBV) from latency into the lytic cycle is associated with the expression of two immediate-early viral genes, BZLF1 and BRLF1. Overexpression of ZEBRA, the product of BZLF1, is sufficient to disrupt latency in B lymphocytes and epithelial cells by stimulating exp...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Ragoczy, Tobias, Heston, Lee, Miller, George
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Virus-Cell Interactions
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110133/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.7978-7984.1998
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