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Altered Plaque Formation by Recombinant Vaccinia Virus Expressing Simian Immunodeficiency Virus Nef

The nef gene of primate lentiviruses encodes a myristoylated protein that is important for pathogenicity and the maintenance of high virus loads. A deletion in nef leads to a significant reduction of the pathogenicity of simian immunodeficiency virus (SIV) in macaques. At the cellular and biochemica...

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Библиографические подробности
Главные авторы: Yamanaka, Miles K., Yilma, Tilahun
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 1998
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC110127/
https://ncbi.nlm.nih.gov/pubmed/9573307
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