Serp2, an Inhibitor of the Interleukin-1β-Converting Enzyme, Is Critical in the Pathobiology of Myxoma Virus

Recently, myxoma virus was shown to encode an additional member of the serpin superfamily. The viral gene, called serp2, was cloned, and the Serp2 protein was shown to specifically bind to interleukin-1β (IL-1β)-converting enzyme (ICE), thus inhibiting the cleavage of pro-IL-1β by the protease (F. P...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Messud-Petit, Frederique, Gelfi, Jacqueline, Delverdier, Maxence, Amardeilh, Marie-France, Py, Robert, Sutter, Gerd, Bertagnoli, Stephane
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110100/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.7830-7839.1998
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