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Structural mechanism of the recovery stroke in the Myosin molecular motor

The power stroke pulling myosin along actin filaments during muscle contraction is achieved by a large rotation (≈60°) of the myosin lever arm after ATP hydrolysis. Upon binding the next ATP, myosin dissociates from actin, but its ATPase site is still partially open and catalytically off. Myosin mus...

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Bibliografiske detaljer
Main Authors: Fischer, Stefan, Windshügel, Björn, Horak, Daniel, Holmes, Kenneth C., Smith, Jeremy C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1100758/
https://ncbi.nlm.nih.gov/pubmed/15863618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408784102
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