Inhibition of Major Histocompatibility Complex Class I Antigen Presentation in Pig and Primate Cells by Herpes Simplex Virus Type 1 and 2 ICP47

Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) express an immediate-early protein, ICP47, that effectively inhibits the human transporter associated with antigen presentation (TAP), blocking major histocompatibility complex (MHC) class I antigen presentation to CD8(+) T cells. Previous work in...

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Bibliographic Details
Main Authors: Jugovic, Pieter, Hill, Ann M., Tomazin, Roman, Ploegh, Hidde, Johnson, David C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110071/
https://ncbi.nlm.nih.gov/pubmed/9573278
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