Lipofection of Purified Adeno-Associated Virus Rep68 Protein: toward a Chromosome-Targeting Nonviral Particle

Adeno-associated virus (AAV) integrates very efficiently into a specific site (AAVS1) of human chromosome 19. Two elements of the AAV genome are sufficient: the inverted terminal repeats (ITRs) and the Rep78 or Rep68 protein. The incorporation of the AAV integration machinery in nonviral delivery sy...

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Bibliographic Details
Main Authors: Lamartina, Stefania, Roscilli, Giuseppe, Rinaudo, Daniela, Delmastro, Paola, Toniatti, Carlo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110032/
https://ncbi.nlm.nih.gov/pubmed/9696870
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