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The Nucleoside Triphosphatase and Helicase Activities of Vaccinia Virus NPH-II Are Essential for Virus Replication

Vaccinia virus NPH-II is the prototypal RNA helicase of the DExH box protein family, which is defined by six shared sequence motifs. The contributions of conserved amino acids in motifs I (TGVGKTSQ), Ia (PRI), II (DExHE), and III (TAT) to enzyme activity were assessed by alanine scanning. NPH-II-Ala...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Gross, Christian H., Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573237/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.4729-4736.1998
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