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Shortening of the Symptom-Free Period in Rhesus Macaques Is Associated with Decreasing Nonsynonymous Variation in the env Variable Regions of Simian Immunodeficiency Virus SIVsm during Passage

During six blood passages of simian immunodeficiency virus SIVsm in rhesus macaques, the asymptomatic period shortened from 18 months to 1 month. To study SIVsm envelope gene (env) evolution during passage in rhesus macaques, the C1 to CD4 binding regions of multiple clones were sequenced at serocon...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Valli, P. J. Spencer, Lukashov, Vladimir V., Heeney, Jonathan L., Goudsmit, Jaap
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.7494-7500.1998
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