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Rotavirus RNA Replication Requires a Single-Stranded 3′ End for Efficient Minus-Strand Synthesis

The segmented double-stranded (ds) RNA genome of the rotaviruses is replicated asymmetrically, with viral mRNA serving as the template for the synthesis of minus-strand RNA. Previous studies with cell-free replication systems have shown that the highly conserved termini of rotavirus gene 8 and 9 mRN...

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Autori principali: Chen, Dayue, Patton, John T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109963/
https://ncbi.nlm.nih.gov/pubmed/9696835
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