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Rotavirus Infection Reduces Sucrase-Isomaltase Expression in Human Intestinal Epithelial Cells by Perturbing Protein Targeting and Organization of Microvillar Cytoskeleton

Rotavirus infection is the most common cause of severe infantile gastroenteritis worldwide. These viruses infect mature enterocytes of the small intestine and cause structural and functional damage, including a reduction in disaccharidase activity. It was previously hypothesized that reduced disacch...

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Autori principali: Jourdan, Nathalie, Brunet, Jean Philippe, Sapin, Catherine, Blais, Anne, Cotte-Laffitte, Jacqueline, Forestier, Françoise, Quero, Anne-Marie, Trugnan, Germain, Servin, Alain L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109945/
https://ncbi.nlm.nih.gov/pubmed/9696817
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