Recombinant Sindbis Viruses Expressing a Cytotoxic T-Lymphocyte Epitope of a Malaria Parasite or of Influenza Virus Elicit Protection against the Corresponding Pathogen in Mice

Subcutaneous administration in mice of recombinant Sindbis viruses expressing a class I major histocompatibility complex-restricted 9-mer epitope of the Plasmodium yoelii circumsporozoite protein or the nucleoprotein of influenza virus induces a large epitope-specific CD8(+) T-cell response. This im...

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Autores principales: Tsuji, Moriya, Bergmann, Cornelia C., Takita-Sonoda, Yoshiko, Murata, Ken-Ichiro, Rodrigues, Elaine G., Nussenzweig, Ruth S., Zavala, Fidel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Viral Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC109904/
https://ncbi.nlm.nih.gov/pubmed/9658144
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