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Cytoplasmic Forms of Human T-Cell Leukemia Virus Type 1 Tax Induce NF-κB Activation

Human T-cell leukemia virus type 1 (HTLV-1) Tax targets I-κBα and I-κBβ for phosphorylation, ubiquitination, and proteasome-mediated degradation, causing the nuclear translocation of NF-κB/Rel proteins and transcription induction of many cellular genes. The mechanism by which a nuclear protein such...

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Bibliografiska uppgifter
Huvudupphovsmän: Nicot, Christophe, Tie, Feng, Giam, Chou-Zen
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC109886/
https://ncbi.nlm.nih.gov/pubmed/9658126
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