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T-Cell Lymphoma Caused by Herpesvirus Saimiri C488 Independently of ie14/vsag, a Viral Gene with Superantigen Homology

The immediate-early gene ie14/vsag of herpesvirus saimiri has homology with murine superantigens. We compared the pathogenesis of infection with either ie14/vsag deletion mutants or wild-type virus C488 in cottontop tamarin monkeys (Saguinus oedipus). Two weeks after infection, all animals developed...

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Detalhes bibliográficos
Main Authors: Knappe, Andrea, Thurau, Mathias, Niphuis, Henk, Hiller, Christian, Wittmann, Sabine, Kuhn, Eva-Maria, Rosenwirth, Brigitte, Fleckenstein, Bernhard, Heeney, Jonathan, Fickenscher, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109857/
https://ncbi.nlm.nih.gov/pubmed/9525684
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