Gastrointestinal T Lymphocytes Retain High Potential for Cytokine Responses but Have Severe CD4(+) T-Cell Depletion at All Stages of Simian Immunodeficiency Virus Infection Compared to Peripheral Lymphocytes

Gastrointestinal complications in human immunodeficiency virus (HIV) infection are indicative of impaired intestinal mucosal immune system. We used simian immunodeficiency virus (SIV)-infected rhesus macaques as an animal model for HIV to determine pathogenic effects of SIV on intestinal T lymphocyt...

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Bibliographic Details
Main Authors: Smit-McBride, Zeljka, Mattapallil, Joseph J., McChesney, Michael, Ferrick, David, Dandekar, Satya
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109855/
https://ncbi.nlm.nih.gov/pubmed/9658111
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