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Neutralizing Antibodies in Sera from Macaques Infected with Chimeric Simian-Human Immunodeficiency Virus Containing the Envelope Glycoproteins of either a Laboratory-Adapted Variant or a Primary Isolate of Human Immunodeficiency Virus Type 1

The magnitude and breadth of neutralizing antibodies raised in response to infection with chimeric simian-human immunodeficiency virus (SHIV) in rhesus macaques were evaluated. Infection with either SHIV-HXB2, SHIV-89.6, or SHIV-89.6PD raised high-titer neutralizing antibodies to the homologous SHIV...

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Published in:J Virol
Main Authors: Montefiori, David C., Reimann, Keith A., Wyand, Michael S., Manson, Kelledy, Lewis, Mark G., Collman, Ronald G., Sodroski, Joseph G., Bolognesi, Dani P., Letvin, Norman L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Viral Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109842/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.3427-3431.1998
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