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Mutations of the Human Immunodeficiency Virus Type 1 p6(Gag) Domain Result in Reduced Retention of Pol Proteins during Virus Assembly

One of the crucial steps in the assembly of the human immunodeficiency virus type 1 (HIV-1) and other retroviruses is the incorporation and retention of all the key viral enzymes in released virions. The viral enzymes protease, reverse transcriptase, and integrase of HIV-1 are initially synthesized...

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Bibliographic Details
Main Authors: Yu, Xiao-Fang, Dawson, Liza, Tian, Chun-Juan, Flexner, Charles, Dettenhofer, Markus
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109837/
https://ncbi.nlm.nih.gov/pubmed/9525672
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