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Herpes Simplex Virus gD and Virions Accumulate in Endosomes by Mannose 6-Phosphate-Dependent and -Independent Mechanisms

Herpes simplex virus (HSV) glycoprotein D (gD) is modified with mannose 6-phosphate (M6P) and binds to M6P receptors (MPRs). MPRs are involved in the well-characterized pathway by which lysosomal enzymes are directed to lysosomes via a network of endosomal membranes. Based on the impaired ability of...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Brunetti, Craig R., Dingwell, Kevin S., Wale, Cathy, Graham, Frank L., Johnson, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.3330-3339.1998
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